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Varisco, PharmD, PhD, an assistant professor in the Department of Pharmaceutical Health Outcomes of Policy and assistant director for Research Development in the Prescription Drug Misuse Education and Research Center at the University of Houston College of Pharmacy

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Originally developed to manage diabetes, these medications have shown powerful effects in reducing appetite, controlling cravings, and supporting long-term fat loss

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Extending beyond 12 weeks requires reassessment if weight loss has plateaued despite adherence to diet and activity, the limiting factor is metabolic adaptation or dietary structure, not insufficient lipotropic support