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After that, they are given once a month to keep levels up

**Pediatric Patients:** Dosage should be determined by a healthcare professional based on the child's age, weight, and clinical condition

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This pattern aligns with B12 pharmacokinetics: serum levels peak 8-12 hours post-injection, tissue saturation occurs over 48-72 hours (Andrs et al., Journal of Blood Medicine , 2018)

Methylcobalamin acts as an essential cofactor in two primary enzyme reactions crucial for human metabolism: Homocysteine to Methionine Conversion: Methylcobalamin is required by the enzyme methionine synthase

Symptoms of Low B12 That Can Look Like Anxiety or Depression One of the challenges with B12 deficiency is that its mood symptoms overlap heavily with primary anxiety and depressive disorders