glp 1 vs 2 vs 3 GLP-1 GLP-2 GLP-3: The Science Behind Modern Metabolic Peptides Frontiers | GLP-1 and GLP-2

1 Introduction Obesity is a progressing and chronic condition defined by Body Mass Index (BMI) over 30 Kg/m2 levels

It plays a pivotal role in glucose metabolism and appetite regulation through multiple mechanisms: Enhances insulin secretion: GLP-1 stimulates pancreatic -cells to release insulin in a glucose-dependent manner Suppresses glucagon: Reduces hepatic glucose production Delays gastric emptying: Creates prolonged satiety Central nervous system effects: Acts on appetite centers in the brain to reduce hunger and food intake Protects pancreatic -cells: Promotes cell proliferation and inhibits apoptosis GLP-1 Receptor Agonists in Clinical Practice GLP-1 receptor agonists (GLP-1 RAs) are medications designed to mimic the action of endogenous GLP-1 but with enhanced pharmacokinetic properties

doi: 10.1016/j.pestbp.2023.105751 62 LiangY.LiangM.ChenH.HongJ.SongY.YueK.et al

Ipamorelin is a selective pentapeptide growth hormone secretagogue composed of five amino acids (Aib-His-D-2-Nal-D-Phe-Lys-NH2)

The peptide encourages actual new vessel growth, expanding the network that feeds your follicles

Available in Raspberry (with Caffeine) and Lemon