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TMAO levels tend to increase with age [6]

This amphipathic nature enables the formation of a fluid bilayer that facilitates membrane dynamics, allowing for vesicular trafficking, membrane fusion, and the movement of membrane proteins

Based on experience in the treatment of other fibrotic diseases, there are a variety of alternative intervention strategies that target the mechanisms in the fibrotic transformation of fibroblast into myofibroblasts such as small molecules or compounds that are currently in clinical trials demonstrating good anti-fibrotic properties (250)

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Federally Qualified Health Centers: HHSN 263201600085U

management is focused on optimizing glycaemic control, the achievement of cardiometabolic targets, and the prevention and/or treatment of diabetic foot complications