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Digestion of h-EGF, h-TGF , and BPC 15 in human gastric juice, Gastroenterology 108 , 761

The presence of the specialized tripeptide KPV allows researchers to monitor the competitive downregulation of nuclear factor kappa B (NF-kB) and trace the inhibition of pro-inflammatory cytokines like tumor necrosis factor-alpha (TNF-alpha) and interleukin-6 (IL-6) within inflamed intestinal or cutaneous tissues

The peptides relatively short 4 to 6 hour half-life supports the theoretical advantage of more frequent administration

95 WangW.HuangZ.HuangL.TanC.ChenW.RoelfsemaF.et al (2021)

J Nutr Sci Vitaminol 1999

Ultrasound findings may not suggest extragastrointestinal involvement