For the complete GHK-Cu research profile, see the Palmetto Peptides Complete Guide to GHK-Cu
Dual Extraction Method This approach captures both water-soluble and alcohol-soluble compounds: Ingredients: 30 grams dried reishi 5 cups filtered water 1 cup vodka or other 80-100 proof alcohol (preferably grain alcohol) Equipment: Stainless steel pot Glass jar with tight-fitting lid Strainer and cheesecloth Amber glass bottles for storage Instructions: Water extraction: Break reishi into small pieces Combine with water in pot Simmer covered for 2 hours until liquid reduces by half Strain and set aside liquid Return mushroom material to pot with 3 cups fresh water Simmer again until reduced by half Strain and combine with first liquid Alcohol extraction: Place used mushroom material in glass jar Add alcohol to completely cover Seal and store in cool, dark place for 2-4 weeks, shaking daily Strain through cheesecloth, squeezing to extract all liquid Combination: Combine both extracts at a ratio of 1:1 Store in amber glass bottles Take by the dropperful or add to hot water to make tea Notes: Most complete extraction of medicinal compounds Alcohol portion extracts triterpenes not soluble in water alone Resulting preparation is shelf-stable for 1-2 years Can be diluted as needed when consuming 4
Human data are extremely limited
Cheng L, Ma F (2004) Diurnal operation of the xanthophyll cycle and the antioxidant system in apple peel
3.3 Dysregulation of host haem-iron homeostasis High iron availability has been shown to increase the pathogenic potential of many bacteria in tissue and animal infection models by enhancing growth, cellular adhesion, invasion and epithelial damage (Reid et al., 2009
Important safety considerations when using these supplements together include: Drug interactions : Berberine may potentially interact with numerous medications, including antidiabetic drugs (increasing hypoglycaemia risk), anticoagulants, and medications metabolised by CYP450 enzymes (such as ciclosporin and certain statins)
