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The significance of hypersialylation of dipeptidyl peptidase IV (CD26) in the inhibition of its activity by Tat and other cationic peptides
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Personalized iPSC-derived dopamine progenitor cells for Parkinsons disease
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Given that both T1DM and T2DM are associated with reduced beta-cell mass and function, these various studies highlight the therapeutic potential of harnessing alpha-cell GLP-1 production to not only stimulate insulin secretion but also promote beta-cell survival and regeneration
Recent studies indicate that mitochondrial dysfunction caused by excessive nutrient supply that overwhelms the Krebs cycle and the mitochondrial respiratory chain may be associated with the development of obesity, oxidative stress, and inflammation [3, 4]
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