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doi: 10.1186/s13075-014-0505-1

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[Note: This reaction is analogous to the formation of cyclic AMP by adenylate cyclase, except that this guanylate cyclase is not membrane associated.] The resultant rise in cGMP causes activation of protein kinase G, which phosphorylates Ca 2+ channels, causing decreased entry of Ca 2+ into smooth muscle cells

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Exploration of molecular mechanism underlying protective effect of astragaloside IV against radiation-induced lung injury by suppressing ferroptosis