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Introduction In 2003, erastin, a novel compound was identified, which showed a selective lethality against human foreskin cells (BJeLR cells) expressing engineered mutated RAS oncogene while using high-throughput screening to find out 23,550 compounds for their ability to eliminate engineered tumorigenic cells (Dolma et al., 2003)

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GLP-1 agonists mimic a hormone

By protecting these compounds from degradation and promoting controlled, targeted release, nano-delivery systems make these polyphenols more effective for use in health and disease management applications