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See all FAQs Important safety information and common side effects The most common side effect of B12 injections is irritation at the injection site

Reduced potency from expired medication may mean your glucose levels are higher than expected

Journal of the American Geriatrics Society 1992;40:1197204

Compounding pharmacies have begun creating formulations that combine tirzepatide with vitamin B12 (cyanocobalamin or methylcobalamin), though these are not FDA-approved combinations

Standard initial treatment for patients: Without neurological involvement: 1000 g intramuscularly three times a week for two weeks

Vitamin injections are administered by trained medical professionals in clinical settings