Sandri M, Sandri C, Gilbert A, Skurk C, Calabria E, Picard A, Walsh K, Schiaffino S, Lecker SH, Goldberg AL (2004) Foxo transcription factors induce the atrophy-related ubiquitin ligase atrogin-1 and cause skeletal muscle atrophy
Synonyms and alternate spellings include: 1-phenylpropan-2-amine (IUPAC name), -methylphenethylamine , amfetamine (International Nonproprietary Name [INN]), -phenylisopropylamine , thyramine , and speed
Jahanian-Najafabadi contributed the initial idea and provided supervision throughout the research process
These systems strategically target intracellular GSH, using it either as a molecular trigger or as a therapeutic target [14]
N-acetylcysteine (NAC) has been shown to treat glutathione deficiency 20 in some studies
Disabling CBP/p300-binding to NRF2 broadly attenuated NRF2 transcriptional activity resulting in an altered metabolic (depletion of glutathione) and lipidomic (specific depletion of triglycerides) cellular landscape