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Indeed, vincristine and verapamil both were shown to decrease the photolabeling of MRP1 by [ 125 I] LY475776, an inhibitor of LTC 4 transport 53

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The most recent Global Burden of Diseases, Injuries, and Risk Factors (GBD) study reported an age-standardized prevalence rate of 448.6 per 100,000 people in 2021 compared to the 2019 editions cited rate of 599 cases per 100,000 people [2,3,4]

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The association of genetically predicted l-carnitine with CAD in men not in women is possibly due to a smaller number of CAD cases in women therefore a lower power (as shown in Additional file 1: Table S6)