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For example, a patient taking once-daily long-acting (basal) insulin and starting a weekly GLP-1RA could be instructed after the second injection of dulaglutide/ semaglutide, every time your fasting glucose level is below [target] mmol/L, reduce your [insulin brand] insulin dose by [10% of dose] units

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DOI: 10.1016/S0026-0495(00)80077-3 9

If you cant tolerate a GLP-1 drug, your doctor might recommend switching to a different weight loss medication