Background GLP-1R agonists protect the blood-brain barrier (BBB): These drugs help maintain the integrity of the BBB by preventing tight junction degradation, which can reduce the risk of neuroinflammation and cognitive decline
Example: You currently inject on Wednesdays
Primary endpoint in expanded populations and high-risk subgroups Semaglutide versus sitagliptin Among patients with obesity and type 2 diabetes at low, moderate or high cardiovascular risk in clinical practice, the 1-year risk of the composite endpoint of myocardial infarction or stroke was 1.5% (95% CI 1.4% to 1.6%) with semaglutide compared to 1.7% (95% CI 1.6% to 1.9%) with sitagliptin
103,104 Thermal-Mechanical EBD Several EBDs deliver thermal-mechanical energy to superficial and deep layers to improve skin quality, laxity, and appearance
Given the small number of studies available for each outcome (k = 3 for AUD
Using the strategies above, Scripius and its health plan partners achieved a year-over-year growth rate in GLP-1 utilization of 18% in 2023.6 Curbing utilization growth in the GLP-1 category will be one key strategy for health plan payers to keep plan costs and premiums as low as possible