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Steps to reduce the risk of and manage metformin-associated lactic acidosis in these high risk groups are provided in the full prescribing information [see Dosage and Administration (2.2), Contraindications (4), Warnings and Precautions (5.1), Drug Interactions (7), and Use in Specific Populations (8.6, 8.7)]

reversal by exendin-4 treatment

GLP-1 slows the rate at which food leaves your stomach and enters the small intestine for absorption

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However, ALA is not considered a standalone solution for weight management