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Key molecular modifications aimed at increasing hydrophobicity and decreasing hydrogen-bonding potential

Wounds displayed faster healing, decreased concentration of metalloproteinases 2 and 9 as well as of TNF- (a major inflammatory cytokine) compared with vehicle alone or with untreated wounds [25]

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In 24 hpi trophozoite-stage parasites, hemoglobin and heme levels were not measurably different, but hemozoin levels were significantly decreased in resistant parasites compared to sensitive parasites (Fig 2B), indicative of decreased turnover of heme into hemozoin in resistant parasites over the preceding 24 h of the parasite lifecycle

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