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Ma et al., 2017

Expression levels were calculated by the delta-delta Ct method

It is not yet known whether mesna also protects against bladder cancer, which can arise about 1020 years after initial treatment with cyclophosphamide

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A healthy, unstressed cell maintains a vast majority of its glutathione pool in the reduced state, typically sustaining a GSH-to-GSSG ratio of greater than 10:1, and often up to 100:1 in the cytosol