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In terms of evidence, insights usually come from three places: randomized trials that catalogue adverse events, real-world observational cohorts that follow patients over time, and pharmacovigilance databases that gather spontaneous reports

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Eur J Nutr (2004) 43(3):12739

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When you overeat while on these medications, food essentially sits in your stomach longer than it would have before, which can lead to uncomfortable fullness, bloating, and even nausea