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People are suing Ozempic, or rather, suing the manufacturer of Ozempic, due to claims that the drug has caused serious side effects and adverse reactions, which they allege were not sufficiently disclosed by Novo Nordisk

FDA issued a Complete Response Letter to Helsinn Therapeutics in 2017 that was never resubmitted (verified 2026-05-19)

Discontinue use and seek healthcare advice if any effects are severe, persistent or concerning

The ranking of therapies is based on their pathway-targeting effectiveness within the DM2-AD comorbidity network, and while metformin demonstrates the highest engagement with key neuroprotective mechanisms, and semaglutide among the least, this does not imply complete inefficacy of lower-ranked therapies

FDA prescribing information for Wegovy defines those conditions as hypertension, type 2 diabetes, dyslipidemia, or obstructive sleep apnea

doi: 10.1097/COC.0000000000000877