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Libby, P., Ridker, P

There is enormous exuberance about starting GLP-1 drugs, but not nearly enough attention to what happens when people stop, said senior author Ziyad Al-Aly, MD, a WashU Medicine clinical epidemiologist and chief of the Research and Development Service at the VA Saint Louis Health Care System

doi: 10.1111/j.1467-789X.2004.00144.x 8 BlherM

For any compound that will be used for decades in chronic disease, a dedicated MACE (major adverse cardiovascular events) trial is required

They also lower glucagon release a hormone that can raise blood glucose [archived link]

Under longstanding federal law, Medicare Part D plans were prohibited from covering drugs used solely for weight loss