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A safe stopping point means you have successfully tapered to the lowest dose or off the medication entirely, while maintaining weight stability, normal appetite signaling, and stable blood sugar control over at least 48 weeks post-discontinuation

When prescribed and monitored by experts, they can become powerful tools for achieving and sustaining fat reduction, renewed energy, and a healthier outlook

To view a copy of this licence, visit About this article Cite this article Quddos, F., Fowler, M., de Lima Bovo, A.C

Participants who stopped semaglutide at week 68 (orange) regained most of their lost weight within a year net loss shrank from 17.3% to 5.6% by week 120

Keeping them separate improves draw accuracy, reduces stopper wear, and limits cross-contamination

Mounjaro represents the next generation, adding a second hormone receptor to the mechanism