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Inflammation modulation

This is also in line with a study in older 16 months old APOE-TR mice which found the same pattern of decreased LCAs and increased SCAs in E4s compared to E3s, particularly in males (Shang et al., 2020)

FLI also predicts NAFLDs extrahepatic complications including cardiometabolic risk, atherosclerosis, T2D, CKD, extrahepatic cancers, and mortality [93] , further supporting a role for GGT as a cardiometabolic biomarker

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However, everything has both sides, copper element exists in a metastable valence state in copper peptides, which results in high reactivity and sensitivity to pH, antioxidants, chelating agents, and other factors [[29], [30], [31]]