Sixty-six participants who achieved a BMI decrease of at least 5% by the end of the run-in phase were randomly assigned 1:1 to 2 mg exenatide extended-release or placebo weekly for 1 year
While GLP-1s are effective for weight loss, they are not clinically appropriate for everyone
One moment, please
In short, there are several reasons why more people and providers are experimenting with microdosing, ranging from cost and access challenges to adverse side effects at standard doses, as well as off-label uses such as appetite suppression, management of acute and chronic inflammation, impulse control, and adjunctive support in type 1 diabetes
Protein and Healthy Fats High-protein meals, especially those with healthy fats, trigger a greater GLP-1 response compared to refined carbohydrates
In those cases the unit math changes a 0.25 mg dose at 3 mg/ml is about 8 units, not 25