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It is worth being clear that this rationale comes from each compounds individual research the combination itself has not been directly tested in a published study

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Insufficient hydration can have negative effects on overall well-being

Facial skin is more delicate and requires different concentrations

This therapy induces ROS generation by triggering direct photochemical reactions, inducing ER stress, or modulating the mitochondrial membrane potential [196]

As is typical for early-phase clinical trials, no formal statistical hypothesis testing or sample size calculation was performed