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coli has the AcrAB-TolC efflux pump, which can pump out -lactams, fluoroquinolones, tetracyclines, and other antibiotics

The establishment of standardized protocols for biomarker assessment in clinical settings remains an ongoing challenge

Side effects are usually mild, such as slight redness or irritation at the injection site

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Among those candidates, we selected four enzyme complexes comprising eleven identified targets for further experimental validation based on the availability of suitable inhibitors