too much tirzepatide (Zepbound) for weight loss TrimRX | What Happens When

Niels V, Curtis BP, Michele MC, Hans-Rudolf B

Body Composition & Fat Reduction Studies demonstrate that NNMT inhibition leads to reduced adiposity and improved metabolic flexibility without the need for stimulant-based interventions

They began micro dosing

Some patients front-load for a few weeks if they're starting from low levels

When semaglutide activates these receptors, it reduces the release of neuropeptide Y (NPY) and AgRP two hormones that stimulate appetite while increasing the activity of POMC neurons, which signal fullness

With this information, your provider can best assess whether tirzepatide is still the best choice for you or if another medication would be a better option