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Certain antibiotics may interact with the cyanocobalamin component through effects on vitamin B12 metabolism or efficacy

doi: 10.1038/s42003-022-03696-z 233 Cardenas-DiazFLOsorio-QuinteroCDiaz-MirandaMAKishoreSLeavensKJobaliyaCet al

However, it may also be administered slowly by intravenous or subcutaneous injection

Requirements of Vitamin B12 in excess of normal (due to pregnancy, thyrotoxicosis, hemolytic anemia, hemorrhage, malignancy, hepatic and renal disease) can usually be met with oral supplementation

The preserved system facilitates repeated access when standard sterile procedures are followed and supports accurate reconstitution steps for lyophilized materials and calibration series in method development

This allows the body to use up any stored vitamin D and the injection can then be administered