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Cochran Abstract The glucagon-like peptide 1 receptor (GLP-1R) is a class B G-protein coupled receptor (GPCR) and diabetes drug target expressed mainly in pancreatic -cells that, when activated by its agonist glucagon-like peptide 1 (GLP-1) after a meal, stimulates insulin secretion and -cell survival and proliferation

Organ Protection Preclinical research demonstrates hepatoprotective, cardioprotective, and neuroprotective effects suggesting benefits that extend beyond musculoskeletal healing

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In a phase III study, semaglutide resulted in greater than 15% weight reduction from baseline (Wadden et al

Front Med (Lausanne) 9:904299

Disease inheritance, HLA type, and immune function