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Published Phase 2 data (Jastreboff et al., New England Journal of Medicine , 2023) demonstrated substantial reductions in body weight and improvements in cardiometabolic markers

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(2006) Acta Crystallogr D Biol Crystallogr 62 : 197-207 PubMed: 16421451 Search on PubMed DOI: Primary Citation Related Structures: 1PKW, 1PKZ, 1PL1, 1PL2, 1XWG PubMed Abstract: Human glutathione transferase A1-1 is a well studied enzyme, but despite a wealth of structural and biochemical data a number of aspects of its catalytic function are still poorly understood

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