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Methods Cell culture, expression constructs, and transfection MIN-6 (purchased from ATCC) cells and GLUTag cells (obtained from Takashi Tsuboi, the university of Tokyo, Japan) were cultured in DMEM with 10% (v/v) heat-inactivated fetal bovine serum

Gender-specific analyzes suggest possible differences in the susceptibility or reliability of the exposure to the biomarker

While L-glutamine was approved by the United States (US) Food and Drug Administration to treat SCD, its impact on the redox environment in sickle erythrocytes is not fully understood

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The median age of patients across all ICSRs was 57 years (range: 1499, n = 2,815), similar to that of each specific GLP-1 RA

However, protocols extending beyond 6 months in humans rely on extrapolation rather than controlled studies