The estrobolome was first described in 2011, and a growing body of research has since shown that it plays a direct role in regulating circulating oestrogen levels through the production of an enzyme called beta-glucuronidase (Baker et al., 2017)
MOTS-c is a mitochondrial-derived peptide being studied for its potential role in metabolism and cellular energy regulation
In the Wolff-Chaikoff effect, excess iodine inhibits iodide trapping, thyroglobulin iodination, and release of thyroid hormone from the gland
Cancer organoid co-culture model system: Novel approach to guide precision medicine
The SELECT trial (Semaglutide Effects on Heart Disease and Stroke in Patients with Overweight or Obesity), completed in 2023 with over 17,600 participants, demonstrated a 20% reduction in major adverse cardiovascular events in patients with established cardiovascular disease and overweight or obesity but without diabetes
while many peptides tolerate saline at reconstitution, the published research-peptide protocols use bacteriostatic water as the consistent standard, and deviating introduces an unknown variable
