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Indeed, the basal oxygen consumption rate (OCR) of Gclc -deficient FoB measured by extracellular flux analysis was slightly reduced compared to Gclc fl/fl FoB (Fig

However, the underlying cause of the deficiency must also be addressed in order to prevent relapse and further complications

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The only benefit may be the possibility of pyruvate decarboxylation by the pyruvate dehydrogenase complex (PDC) [96], which produces the equimolar amount of NADH

Losurdo G, Salvatore DAbramo F, Indellicati G, Lillo C, Ierardi E, Di Leo A

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