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first triple combination for the initial treatment of hypertension Triple therapy combination containing an angiotensin II receptor blocker (telmisartan), a dihydropyridine calcium channel blocker (amlodipine) and a thiazide-like diuretic (indapamide) Indicated for the treatment of hypertension, including as initial treatment, to lower blood pressure (lowering blood pressure reduces the risk of fatal and nonfatal cardiovascular [CV] events, primarily strokes and myocardial infarctions [MIs]) Oral fixed-dose tablets (telmisartan/amlodipine/indapamide): 10 mg/1.25 mg/0.625 mg, 20 mg/2.5 mg/1.25 mg and 40 mg/5 mg/2.5 mg Recommended initial dosage is the lowest or middle tablet strength orally once daily

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For patients also considering tirzepatide as an alternative, our Mounjaro vs Ozempic vs Wegovy comparison provides a useful clinical overview

In Pevec et al.s rat model study, crushed gastrocnemius muscle complexes in untreated controls showed minimal spontaneous recovery