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Phytoprostanes (Plant Isoprostanes) In plants subjected to biotic and abiotic stresses, -linolenic acid is the precursor of oxygenated fatty acids and C 18 isoprostanoids (dinor-isoprostanes or phytoprostanes) via non-enzymatic, free radical-catalysed pathways as for isoprostane synthesis in animals but with singlet oxygen ( 1 O 2 or O=O) generated in chloroplasts during photosynthesis as the most important reactive oxygen species (ROS)
From a basic science standpoint, acetylcysteine neutralizes NAPQI in a 1:1 molar ratio, so the dose of acetylcysteine should be scaled up in proportion to the amount of acetaminophen