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Iron malabsorption can also be due to gastrointestinal disorders of autoimmune etiology (celiac disease, atrophic gastritis, IBD), which are often associated with autoimmune thyroid diseases [59, 60]

In cancer, inducers of ferroptosis, such as erastin and RSL3, take advantage of the high levels of iron and PUFAs in tumor cells [94, 95], while inhibitors like fer-1 and liproxstatin-1 show potential in treating neurodegenerative diseases, including Alzheimers, where lipid peroxidation contributes to neuronal damage [96]

Instead, you begin low and increase gradually over weeks or months

Free radical scavengers -such as glutathione -that restore the structure and function of poly-unsaturated fatty acids (PUFA) in the cell membrane, can be used to treat these cases

(Phila) 2014;7:319329

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