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Most people with endogenous excess uric acid production appear to have a salvage pathway, and FA promotes uric acid synthesis through the purine salvage pathway by activating hypoxia-inducible factor-1 (HIF-1) to upregulate the expression of purine metabolism-related enzymes (100102)

EvansMCoganKEEganB.Metabolism of ketone bodies during exercise and training: Physiological basis for exogenous supplementation

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DSIP's relatively short in vitro stability due to enzymatic degradation distinguishes it from more stabilized peptide analogs, making it a useful model for studying peptide metabolism and signaling kinetics