Using BOTOX with certain other medicines may cause serious side effects
Learn more about the GnRH antagonists Orilissa, Oriahnn, and Myfembree
Usually stabilizes
Extra caution is advised in people with: A history of pancreatitis Severe acidity or gastroparesis (very slow stomach emptying) Known gallstones or gallbladder disease Advanced kidney disease Significant diabetic eye disease (retinopathy) A very low BMI or a history of eating disorders Pregnancy, plans to become pregnant, or breastfeeding, since some GLP-1 medicines stay in the body for several weeks after stopping Significant depression, who should be monitored carefully Upcoming surgery, endoscopy, or a procedure needing anaesthesia or sedation, since delayed stomach emptying can raise aspiration risk and temporary stopping may be advised How GLP-1 side effects usually progress: a typical timeline Every person is different, but clinical practice and studies suggest a rough pattern [6]: First 2 to 6 weeks: nausea, early fullness, and constipation are most common

This is believed to be down to body composition, as women typically have a higher body fat percentage and female-specific hormones, which may interact with the drug differently
It's also important to remember that diet drives most long-term changes in body composition