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Another intriguing approach is using microbial metabolites as adjuncts: as mentioned, oral propionate supplementation led to fewer relapses and increased Tregs in a cohort of MS patients [206]

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Fmr1KO mice exhibit increased power of high-frequency gamma oscillations under auditory stimulation, along with impaired working memory, reduced sociability, and anxiety-like behavior

Bioidentical Hormone Therapy (BHT): Using bioidentical estrogen and progesterone to smooth out the wild fluctuations and restore metabolic function

No large human randomized controlled trial exists for either compound in any musculoskeletal use

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