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On the other hand, the multi-receptor agonists currently in development (tirzepatide targeting GIP/GLP-1, retatrutide targeting GIP/GLP-1/glucagon, survodutide targeting glucagon/GLP-1) have shown that engaging multiple incretin and related pathways can produce greater weight loss and broader metabolic benefits than GLP-1 agonism alone

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Mainly present in the heart and muscle cells of our body, L-Carnitine also helps to decrease muscle lactate, to enhance the use of glucose, to increase the use of lipids as an energy substrate, to stabilize the cell membrane and to express certain genes related to lipid catabolism

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