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Circulating levels decline with agefrom ~200 ng/mL at age 20 to ~80 ng/mL by age 60correlating with decreased regenerative capacity

Similarly, bifidobacteria synthesize folate de novo or from precursors or, on the contrary, do not synthesize but utilize available folate depending on the respective strain and medium composition

Second, ingested collagen peptides are absorbed and then eliminated: they are repetitive nutritional signals, not permanent "stocks"

This combination is often discussed in wellness and regenerative medicine settings because patients are interested in tissue support, recovery support, mobility, and post-activity recovery

K.ItamuraR.NishiyamaN.et al (2004)