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As a result, these products remain unapproved in the U.S., leaving clinicians with limited treatment options for interstitial cystitis

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Official Guidance and Warnings While the Zepbound warning label clearly states that severe stomach problems are a possible serious side effect and recommends against use in patients with existing gastroparesis, it does not explicitly list new stomach paralysis or gastroparesis as potential risks that can be caused by the drug in all patients