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Lih-Brody L, Powell SR, Collier KP, et al

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The least-squares mean percentage change in body weight from baseline was -7.2% in the 1 mg group, -12.9% in the 4 mg group (starting at 2 mg), -17.1% in the combined 4 mg groups, -17.5% in the combined 8 mg groups, and -17.5% in the 12 mg group, compared with -1.6% in the placebo group

Emerging trends in pain modulation by metabotropic glutamate receptors