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Knudsen chose to use palmitic acid which is one of the most common fatty acids found in the body (Holst 2024

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A yellow or discoloured tint compared to a new vial

Clinical trial data from the NEJM Phase 2 study showed that gastrointestinal events were predominantly mild to moderate, occurred primarily during dose escalation, and were partially mitigated by starting at 2mg rather than 4mg

This compounded effect increases the risk of constipation, bowel obstruction, and abdominal pain