For most patients in clinical trials, GI side effects were described as mild-to-moderate and transient
They found that diabetic patients had a significantly increased risk (double) compared to non-users
The Phase 2 dose-finding trial (N=338), published in the New England Journal of Medicine in 2023 (DOI: 10.1056/NEJMoa2301972), randomized participants with obesity (BMI 30-50) to retatrutide at doses ranging from 0.5mg to 12mg weekly or placebo over 48 weeks
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Im sorry to hear about your plantar fascia rupture and ongoing issues