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Start exercising with low-impact activity, and once you can work out for 30 minutes or more, try higher-intensity workouts and weight lifting

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That volume works for a short-term rodent metabolic model, a three to four point dose-response curve, or a cell-based assay studying glucose-dependent insulin secretion, glucagon suppression, or gastric motility

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Clinical results : Participants typically lose 5-10% of body weight over one year

The effect was initially thought to be secondary to reduced gastric emptying, however, it was later shown to be an independent effect (227, 228)