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These mechanisms are driving each other in a continuous feedback loopand addressing any one of them in isolation, while ignoring the others, produces limited results
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Briefly, Mercury(II) ions present in the environment cross the microorganisms cellular membrane and are scavenged by MerA, a homo-dimeric enzyme which sandwiches the Hg 2+ between a pair of catalytically essential cysteine thiol groups, to make a protein-embedded mercury(II)-bis-thiolate
[DOI] [PubMed] [Google Scholar] 55.Karve SJ, Feldman SR, Yentzer BA, Pearce DJ, Balkrishnan R
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