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Pyruvate is mostly converted into lactate rather than transferred into mitochondria

Long-acting GLP-1RA reduces blood sugar by stimulating and activating GLP-1R for a prolonged period, promoting the secretion of insulin and inhibiting the secretion of glucagon, and it has a limited effect on postprandial blood sugar fluctuations

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Antibiotics also could improve the safety profile of some drugs, for example, the deleterious effects of olanzapine, an antipsychotic medication known for predisposing to metabolic disorder, were attenuated with antibiotics co-treatment [38]

7, 8 References 1 LeRoith, D., Holly, J