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Among the 25 studies included in the qualitative synthesis (16 in the meta-analysis), 15 focused specifically on serum cobalamin changes (reported by baseline and post-treatment means and standard deviations in pg/mL) and 10 reported homocysteine outcomes (means and standard deviations in mmol/L)

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In addition, the mitochondrial membrane is also a significant source of ROS

[DOI] [PMC free article] [PubMed] [Google Scholar] Patel M, Tang BK, Kalow W

A cancer treatment strategy that involves conjugation of a prodrug-activating enzyme (such as cytosine deaminase, which converts the non-toxic prodrug 5-fluorocytosine to the anticancer drug 5-fluorouracil) to a tumour-targeting antibody