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It mimics two hormones produced in the gut GIP (glucose-dependent insulinotropic polypeptide) and GLP-1 (glucagon-like peptide-1) - both of which help manage blood sugar and appetite

This coincided with downregulation of hepatic lipogenesis genes (ACC, ACC, FASN) and upregulation of PPAR (fatty acid oxidation), suggesting semaglutide drives the liver away from storing fat and toward burning it [39]

In this article, well break down

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