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The nuclear complexes that form change the expression of estrogen-dependent genes to generate multiple growth-promoting signals both inside and outside the nucleus

Journal of the Endocrine Society , 5(Suppl 1)

Tirzepatide (Mounjaro, Zepbound) is a dual GIP/GLP-1 receptor agonist approved for type 2 diabetes and chronic weight management, but concerns about tirzepatide and thyroid nodules have emerged from animal studies showing thyroid C-cell tumors in rodents

J Psychosom Obstet Gynecol

Researchers also reported that cancer patients receiving immunotherapies such as Merck's Keytruda and Bristol Myers Squibb's Opdivo or Yervoy appeared to fare better when they were taking GLP-1 drugs, suggesting a possible interaction with the immune system